Foot and Mouth Disease Vaccine Challenge Project

In Progress

SUMMARY

The AgResults Foot and Mouth Disease Vaccine Challenge Project is an eight-year, US$17.34 million prize competition that encourages the development and uptake of high-quality FMD vaccines tailored to meet the needs of Eastern Africa. The prize is structured as a cost-share that reduces the cost-per-dose for buyers, enabling public and private sector actors to better combat FMD through more consistent purchases of these vaccines. In this way, the project can create a market around an effective solution that will improve animal health and strengthen farmer livelihoods. GALVmed serves as the Project Manager.

For more detailed information about the FMD Vaccine Challenge Project and resources for competitors, visit the FMD Project page, managed by GALVmed.

man injecting a cow with FMD vaccine
The FMD Vaccine project encourages the development and uptake of high-quality FMD vaccines for Eastern Africa.

THE LEARNING JOURNEY


THE PROBLEM

A Need for a High-Quality Solution and Strong Distribution Networks

FMD control in Eastern Africa is hindered by two interconnected challenges: a need for a high-quality solution and for stronger distribution networks. First, FMD strains vary significantly in the region, making it difficult to develop an appropriate vaccine. Vaccines currently in use do not contain representative strains from all four serotypes circulating in the region, limiting their ability to provide protection against FMD.

Second, the private sector has struggled to establish distribution networks. National governments currently control FMD vaccine purchases and are often reactive, creating unreliable market demand and hinging on political priorities. These factors combine to limit profitability and discourage investment among potential private sector players to manufacture and distribute vaccines.


CONTEST DESIGN

Theory of Change

The project’s Theory of Change hypothesizes that by creating an attractive market for FMD vaccines tailored to Eastern Africa, private sector manufacturers will be encouraged to develop a regionally relevant FMD vaccine. AgResults will work with private and public sector buyers to increase regional purchases and work towards a stable FMD vaccine market.

Once vaccines are developed and registered, the focus will shift to supporting the adoption of the approved vaccines in the region. AgResults has established a cost-share mechanism that will reduce the cost-per-dose for both public and private sector vaccine purchases. A subset of these vaccines will be earmarked for private sector purchase; at the same time, the project will work via donors to encourage government reform to liberalize the vaccine market. The combinations of these actions will further enable private sector distribution, driving the sales and reach of effective FMD vaccines, particularly among smallholder farmers. As sales volumes rise and prices fall, access will continue to climb, improving animal health and strengthening farmer livelihoods.


EXPECTED IMPACT

The project is expected to incentivize manufacturers to support long-term efforts to control FMD by showing them the economic benefits of investing in the development and distribution of a vaccine that is regionally relevant and high-quality. By developing a stable market around FMD control, smallholder farmers should more easily access the vaccine, in turn reducing losses in productivity and livestock among smallholder farmers.

The project should impact vaccine users as well as public and private sector buyers: Demand for the vaccine among smallholder and commercial farmers is expected to rise as they see the merits of an effective solution. Similarly, both public and private sector buyers are expected to invest in developing distribution networks to reach the growing market.


EVALUATION

Evaluation Design

The evaluation for the FMD vaccine prize competition, led by IDinsight, uses a mixed-methods approach. This mixed-methods evaluation will primarily use Process Tracing to assess the degree to which the development and cost-share incentive stimulates the introduction of high-quality FMD vaccines to Eastern Africa, increases vaccine uptake by public and private sector entities, and influences government policy. This analysis will draw on three rounds of interviews from vaccine manufacturers; government policymakers and distributors; multilateral and non-governmental organizations; the AgResults implementers; and other expert sources, as well as on survey data collected at the end of the project from smallholder farmers.

Evaluation Stage

External Evaluator IDinsight completed a baseline report for the process tracing in 2021 and is currently conducting the midline round of data collection. The Evaluator plans to conduct the endline and share findings in 2028.


LEARNING

What We’ve Learned through Implementation

This section shares our learning from the Foot and Mouth Disease Vaccine Challenge Project design and implementation. Further details can be found in the Learning Library.

Relevant News and Blog

A technician works in an animal health laboratory.

A Conversation about Foot and Mouth Disease with Biopharma

April 15, 2025

In August 2024, by successfully registering its quadrivalent Foot and Mouth Disease (FMD) vaccine tailored for Eastern Africa,…

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A Milestone in the Journey to Create an Effective Foot and Mouth Disease (FMD) Vaccine for Eastern Africa

September 25, 2024

On September 24, the AgResults FMD Vaccine Challenge Project held an event at the FAO Global Conference on…

agresults logo

Request for Proposals for Verifier Services for the FMD Vaccine Challenge Project

June 3, 2024

The Secretariat of AgResults (“Secretariat”) invites your organization to submit a proposal (“Proposal”) to provide verification services in…

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Developing a Public Private Partnership Framework for FMD in Eastern Africa

October 28, 2021

by Badi Maulidi, GALVmed This post was originally published on the GALVmed website. Although Public Private Partnerships (PPPs) have…

two men who are veterinarians looking at a cow

Reflections on how Public-Private Partnerships Can Address FMD in Eastern Africa

September 3, 2020

Paul Kararu Mathai, farmer, together with Dr Christopher Auma, veterinarian working for Nakuru County Government, at Paul's farm,…

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A Step Forward with FMD Public-Private Partnerships in Eastern Africa

August 3, 2020

Dr Kellen Asena and Dennis Tonui to give cows the East Coast Fever vaccine at a farm near…

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New AgResults Project Encourages FMD Vaccine Development and Uptake in Eastern Africa

January 24, 2020

On January 22, the AgResults Foot and Mouth Disease (FMD) Vaccine Challenge Project, which uses a prize competition…


Project Team

head shot of Badi

Badi Maulidi

GALVmed – Buyer Relations Lead

Currently the Buyer Relations Lead for the AgResults Foot and Mouth Disease (FMD) Vaccine Challenge Project, Badi Maulidi has more than 18 years of commercial experience in the pharmaceutical, FMCG and agricultural sectors. Mr. Maulidi started his career in front-line sales, marketing, and key accounts management, and has progressed to strategic business management, enterprise consulting and project management roles. He holds a BSc in Animal Production and an MBA in Entrepreneurship & Innovation Management

head shot photo of Jeffrey Hammond

Jeffrey Hammond

GALVmed – FMD Industry Expert

Currently the FMD Industry Expert for the AgResults Foot and Mouth Disease (FMD) Vaccine Challenge Project, Jeffrey Hammond is a recognized global expert in FMD whose past experience includes: Head of the World Reference Laboratory for Foot and Mouth Disease at the Pirbright Laboratory; Co-Founder of the Global Foot and Mouth Disease Research Alliance (GFRA); and Vice-President of the Scientific Commission for Animal Diseases at the OIE, Paris. Mr. Hammond holds an Honours Degree in Immunology and a PhD in the Molecular Virology of African Swine Fever Virus.

head shot photo of Nina Henning

Nina Henning

GALVmed – Team Lead

Currently the Project Manager Team Lead for the AgResults Foot and Mouth Disease (FMD) Vaccine Challenge Project, Nina Henning is an experienced senior manager with more than 15 years of leadership experience in Africa and South Asia across multinational SME, nonprofit, and investment entities. Prior to joining GALVmed, Ms. Henning oversaw the conceptualization and commercialization of several social businesses for SC Johnson, focused on delivery of low-cost malaria preventative products in Sub-Saharan Africa. She holds a BA from Princeton University, and an MBA/MSc from the University of Michigan.